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Microfluidic neurite guidance to study structure-function relationships in topologically-complex population-based neural networks

The central nervous system is a dense, layered, 3D interconnected network of populations of neurons, and thus recapitulating that complexity for in vitro CNS models requires methods that can create defined topologically-complex neuronal networks. Several three-dimensional patterning approaches have...

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Detalles Bibliográficos
Autores principales: Honegger, Thibault, Thielen, Moritz I., Feizi, Soheil, Sanjana, Neville E., Voldman, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916598/
https://www.ncbi.nlm.nih.gov/pubmed/27328705
http://dx.doi.org/10.1038/srep28384