Comparative metabolomics profiling of isogenic KRAS wild type and mutant NSCLC cells in vitro and in vivo

Oncogenes induce metabolic reprogramming on cancer cells. Recently, G12C KRAS mutation in isogenic NSCLC cell line has been shown to be a key player in promoting metabolic rewiring mainly through the regulation of glutamine metabolism to fuel growth and proliferation. Even though cell lines possessi...

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Detalles Bibliográficos
Autores principales: Brunelli, Laura, Caiola, Elisa, Marabese, Mirko, Broggini, Massimo, Pastorelli, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916601/
https://www.ncbi.nlm.nih.gov/pubmed/27329432
http://dx.doi.org/10.1038/srep28398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916601/
https://www.ncbi.nlm.nih.gov/pubmed/27329432
http://dx.doi.org/10.1038/srep28398

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