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Specification of jaw identity by the Hand2 transcription factor

Acquisition of the lower jaw (mandible) was evolutionarily important for jawed vertebrates. In humans, syndromic craniofacial malformations often accompany jaw anomalies. The basic helix-loop-helix transcription factor Hand2, which is conserved among jawed vertebrates, is expressed in the neural cre...

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Detalles Bibliográficos
Autores principales: Funato, Noriko, Kokubo, Hiroki, Nakamura, Masataka, Yanagisawa, Hiromi, Saga, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916603/
https://www.ncbi.nlm.nih.gov/pubmed/27329940
http://dx.doi.org/10.1038/srep28405