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The Prefrontal Dectin-1/AMPA Receptor Signaling Pathway Mediates The Robust and Prolonged Antidepressant Effect of Proteo-β-Glucan from Maitake

Proteo-β-glucan from Maitake (PGM) is a strong immune regulator, and its receptor is called Dectin-1. Cumulative evidence suggests that AMPA receptors are important for the treatment of depression. Here, we report that PGM treatment leads to a significant antidepressant effect in the tail suspension...

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Detalles Bibliográficos
Autores principales: Bao, Hongkun, Ran, Pengzhan, Zhu, Ming, Sun, Lijuan, Li, Bai, Hou, Yangyang, Nie, Jun, Shan, Liping, Li, Hongliang, Zheng, Shangyong, Xu, Xiufeng, Xiao, Chunjie, Du, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916609/
https://www.ncbi.nlm.nih.gov/pubmed/27329257
http://dx.doi.org/10.1038/srep28395