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The Prefrontal Dectin-1/AMPA Receptor Signaling Pathway Mediates The Robust and Prolonged Antidepressant Effect of Proteo-β-Glucan from Maitake
Proteo-β-glucan from Maitake (PGM) is a strong immune regulator, and its receptor is called Dectin-1. Cumulative evidence suggests that AMPA receptors are important for the treatment of depression. Here, we report that PGM treatment leads to a significant antidepressant effect in the tail suspension...
Autores principales: | Bao, Hongkun, Ran, Pengzhan, Zhu, Ming, Sun, Lijuan, Li, Bai, Hou, Yangyang, Nie, Jun, Shan, Liping, Li, Hongliang, Zheng, Shangyong, Xu, Xiufeng, Xiao, Chunjie, Du, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916609/ https://www.ncbi.nlm.nih.gov/pubmed/27329257 http://dx.doi.org/10.1038/srep28395 |
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