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Futures Challenges in Thyroid Hormone Signaling Research

The canonical pathway of thyroid hormone signaling involves its binding to nuclear receptors (TRs) acting directly on the transcription of a number of genes. Recent genome-wide studies revealed that chromatin occupancy by TR is not sufficient for transactivation of gene expression. Reciprocally, in...

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Detalles Bibliográficos
Autor principal: Flamant, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916735/
https://www.ncbi.nlm.nih.gov/pubmed/27445973
http://dx.doi.org/10.3389/fendo.2016.00058