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An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes

Brown adipose tissue is a promising therapeutic target for opposing obesity, glucose intolerance and insulin resistance. The ability to modulate gene expression in mature brown adipocytes is important to understand brown adipocyte function and delineate novel regulatory mechanisms of non-shivering t...

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Detalles Bibliográficos
Autores principales: Isidor, Marie S., Winther, Sally, Basse, Astrid L., Petersen, M. Christine H., Cannon, Barbara, Nedergaard, Jan, Hansen, Jacob B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916873/
https://www.ncbi.nlm.nih.gov/pubmed/27386153
http://dx.doi.org/10.1080/21623945.2015.1111972