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Prelamin A processing, accumulation and distribution in normal cells and laminopathy disorders

Lamin A is part of a complex structural meshwork located beneath the nuclear envelope and is involved in both structural support and the regulation of gene expression. Lamin A is initially expressed as prelamin A, which contains an extended carboxyl terminus that undergoes a series of post-translati...

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Detalles Bibliográficos
Autores principales: Casasola, Andrea, Scalzo, David, Nandakumar, Vivek, Halow, Jessica, Recillas-Targa, Félix, Groudine, Mark, Rincón-Arano, Héctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916894/
https://www.ncbi.nlm.nih.gov/pubmed/26900797
http://dx.doi.org/10.1080/19491034.2016.1150397