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Consensus protein design

A popular and successful strategy in semi-rational design of protein stability is the use of evolutionary information encapsulated in homologous protein sequences. Consensus design is based on the hypothesis that at a given position, the respective consensus amino acid contributes more than average...

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Detalles Bibliográficos
Autores principales: Porebski, Benjamin T., Buckle, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917058/
https://www.ncbi.nlm.nih.gov/pubmed/27274091
http://dx.doi.org/10.1093/protein/gzw015