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Novel Computational Protocols for Functionally Classifying and Characterising Serine Beta-Lactamases
Beta-lactamases represent the main bacterial mechanism of resistance to beta-lactam antibiotics and are a significant challenge to modern medicine. We have developed an automated classification and analysis protocol that exploits structure- and sequence-based approaches and which allows us to propos...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917113/ https://www.ncbi.nlm.nih.gov/pubmed/27332861 http://dx.doi.org/10.1371/journal.pcbi.1004926 |