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Eyedrop Vaccination Induced Systemic and Mucosal Immunity against Influenza Virus in Ferrets

We investigated eyedrop vaccination (EDV) in pre-clinical development for immunological protection against influenza and for potential side effects involving ocular inflammation and the central nervous system (CNS). Live attenuated influenza EDV, CA07 (H1N1), PZ-4 (H1N2) and Uruguay (H3N2), induced...

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Detalles Bibliográficos
Autores principales: Yoon, Sangchul, Kim, Eun-Do, Song, Min-Suk, Han, Soo Jung, Park, Tae Kwann, Choi, Kyoung Sub, Choi, Young-Ki, Seo, Kyoung Yul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917170/
https://www.ncbi.nlm.nih.gov/pubmed/27333331
http://dx.doi.org/10.1371/journal.pone.0157634