Anticancer Effects of Paris Saponins by Apoptosis and PI3K/AKT Pathway in Gefitinib-Resistant Non-Small Cell Lung Cancer

BACKGROUND: Paris saponins have been studied for their anticancer effects in various cancer types, but the mechanisms underlying the cytotoxic effects, especially in EGFR-TKI-resistant cells, are still unclear. We explored the potential mechanism of the antitumor effects of PSI, II, VI, VII in EGFR-...

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Detalles Bibliográficos
Autores principales: Zhu, Xinhai, Jiang, Hao, Li, Jinhui, Xu, Ji, Fei, Zhenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917328/
https://www.ncbi.nlm.nih.gov/pubmed/27125283
http://dx.doi.org/10.12659/MSM.898558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917328/
https://www.ncbi.nlm.nih.gov/pubmed/27125283
http://dx.doi.org/10.12659/MSM.898558

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