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Anticancer Effects of Paris Saponins by Apoptosis and PI3K/AKT Pathway in Gefitinib-Resistant Non-Small Cell Lung Cancer
BACKGROUND: Paris saponins have been studied for their anticancer effects in various cancer types, but the mechanisms underlying the cytotoxic effects, especially in EGFR-TKI-resistant cells, are still unclear. We explored the potential mechanism of the antitumor effects of PSI, II, VI, VII in EGFR-...
Autores principales: | Zhu, Xinhai, Jiang, Hao, Li, Jinhui, Xu, Ji, Fei, Zhenghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917328/ https://www.ncbi.nlm.nih.gov/pubmed/27125283 http://dx.doi.org/10.12659/MSM.898558 |
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