Combined Intraperitoneal and Intrathecal Etanercept Reduce Increased Brain Tumor Necrosis Factor-Alpha and Asymmetric Dimethylarginine Levels and Rescues Spatial Deficits in Young Rats after Bile Duct Ligation

Background: Rats subjected to bile duct ligation (BDL) exhibit increased systemic oxidative stress and brain dysfunction characteristic of hepatic encephalopathy (HE), including fatigue, neurotransmitter alterations, cognitive and motor impairment, and brain inflammation. The levels of tumor necrosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheen, Jiunn-Ming, Chen, Yu-Chieh, Hsu, Mei-Hsin, Tain, You-Lin, Yu, Hong-Ren, Huang, Li-Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917524/
https://www.ncbi.nlm.nih.gov/pubmed/27445694
http://dx.doi.org/10.3389/fncel.2016.00167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917524/
https://www.ncbi.nlm.nih.gov/pubmed/27445694
http://dx.doi.org/10.3389/fncel.2016.00167

Ejemplares similares