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Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval

There has been a growing interest in the study of epigenetic mechanisms to elucidate the molecular bases of human brain-related diseases and disorders. Frequently, researchers utilize post-mortem tissue with the assumption that post-mortem tissue decay has little or no effect on epigenetic marks. Al...

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Detalles Bibliográficos
Autores principales: Gross, Jeffrey A., Nagy, Corina, Lin, Li, Bonneil, Éric, Maheu, Marissa, Thibault, Pierre, Mechawar, Naguib, Jin, Peng, Turecki, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917525/
https://www.ncbi.nlm.nih.gov/pubmed/27446202
http://dx.doi.org/10.3389/fgene.2016.00120