Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis

Pulmonary fibrosis is pathologic remodeling of lung tissue that can result in difficulty breathing, reduced quality of life, and a poor prognosis for patients. Fibrosis occurs as a result of insult to lung tissue, though mechanisms of this response are not well-characterized. The disease is driven i...

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Detalles Bibliográficos
Autores principales: Warsinske, Hayley C., Wheaton, Amanda K., Kim, Kevin K., Linderman, Jennifer J., Moore, Bethany B., Kirschner, Denise E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917547/
https://www.ncbi.nlm.nih.gov/pubmed/27445819
http://dx.doi.org/10.3389/fphar.2016.00183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917547/
https://www.ncbi.nlm.nih.gov/pubmed/27445819
http://dx.doi.org/10.3389/fphar.2016.00183

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