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C-Type Natriuretic Peptide Induces Anti-contractile Effect Dependent on Nitric Oxide, Oxidative Stress, and NPR-B Activation in Sepsis

Aims: To evaluate the role of nitric oxide, reactive oxygen species (ROS), and natriuretic peptide receptor-B activation in C-type natriuretic peptide-anti-contractile effect on Phenylephrine-induced contraction in aorta isolated from septic rats. Methods and Results: Cecal ligation and puncture (CL...

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Detalles Bibliográficos
Autores principales: Pernomian, Laena, Prado, Alejandro F., Silva, Bruno R., Azevedo, Aline, Pinheiro, Lucas C., Tanus-Santos, José E., Bendhack, Lusiane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917550/
https://www.ncbi.nlm.nih.gov/pubmed/27445832
http://dx.doi.org/10.3389/fphys.2016.00226