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Abnormal Development of Glutamatergic Synapses Afferent to Dopaminergic Neurons of the Pink1(−/−) Mouse Model of Parkinson’s Disease

In a preceding study, we showed that in adult pink1(−/−) mice, a monogenic animal model of Parkinson’s disease (PD), striatal neurons display aberrant electrical activities that precede the onset of overt clinical manifestations. Here, we tested the hypothesis that the maturation of dopaminergic (DA...

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Detalles Bibliográficos
Autores principales: Pearlstein, Edouard, Michel, François J., Save, Laurène, Ferrari, Diana C., Hammond, Constance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917553/
https://www.ncbi.nlm.nih.gov/pubmed/27445695
http://dx.doi.org/10.3389/fncel.2016.00168