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Ischemic postconditioning protects the heart against ischemia–reperfusion injury via neuronal nitric oxide synthase in the sarcoplasmic reticulum and mitochondria

As a result of its spatial confinement in cardiomyocytes, neuronal nitric oxide synthase (nNOS) is thought to regulate mitochondrial and sarcoplasmic reticulum (SR) function by maintaining nitroso-redox balance and Ca(2+) cycling. Thus, we hypothesize that ischemic postconditioning (IPostC) protects...

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Detalles Bibliográficos
Autores principales: Hu, L, Wang, J, Zhu, H, Wu, X, Zhou, L, Song, Y, Zhu, S, Hao, M, Liu, C, Fan, Y, Wang, Y, Li, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917647/
https://www.ncbi.nlm.nih.gov/pubmed/27171264
http://dx.doi.org/10.1038/cddis.2016.108