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Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer

Resveratrol has various attractive bioactivities, such as prevention of cancer, neurodegenerative disorders, and obesity-related diseases. Therefore, identifying its direct binding proteins is expected to discover druggable targets. Sirtuin 1 and phosphodiesterases have so far been found as the dire...

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Detalles Bibliográficos
Autores principales: Taniguchi, T, Iizumi, Y, Watanabe, M, Masuda, M, Morita, M, Aono, Y, Toriyama, S, Oishi, M, Goi, W, Sakai, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917653/
https://www.ncbi.nlm.nih.gov/pubmed/27148684
http://dx.doi.org/10.1038/cddis.2016.114