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Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer
Resveratrol has various attractive bioactivities, such as prevention of cancer, neurodegenerative disorders, and obesity-related diseases. Therefore, identifying its direct binding proteins is expected to discover druggable targets. Sirtuin 1 and phosphodiesterases have so far been found as the dire...
Autores principales: | Taniguchi, T, Iizumi, Y, Watanabe, M, Masuda, M, Morita, M, Aono, Y, Toriyama, S, Oishi, M, Goi, W, Sakai, T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917653/ https://www.ncbi.nlm.nih.gov/pubmed/27148684 http://dx.doi.org/10.1038/cddis.2016.114 |
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