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GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation

Growth arrest and DNA damage inducible protein 34 (GADD34) is induced by various cellular stresses, such as DNA damage, endoplasmic reticulum stress, and amino-acid deprivation. Although the major roles of GADD34 are regulating ER stress responses and apoptosis, a recent study suggested that GADD34...

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Detalles Bibliográficos
Autores principales: Ito, S, Tanaka, Y, Oshino, R, Okado, S, Hori, M, Isobe, K-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917654/
https://www.ncbi.nlm.nih.gov/pubmed/27171261
http://dx.doi.org/10.1038/cddis.2016.116