Transcription factor Six2 mediates the protection of GDNF on 6-OHDA lesioned dopaminergic neurons by regulating Smurf1 expression

Glial cell line-derived neurotrophic factor (GDNF) has strong neuroprotective and neurorestorative effects on dopaminergic (DA) neurons in the substantia nigra (SN); however, the underlying molecular mechanisms remain to be fully elucidated. In this study, we found that the expression level of trans...

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Detalles Bibliográficos
Autores principales: Gao, J, Kang, X-y, Sun, S, Li, L, Zhang, B-l, Li, Y-q, Gao, D-s
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917658/
https://www.ncbi.nlm.nih.gov/pubmed/27148690
http://dx.doi.org/10.1038/cddis.2016.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917658/
https://www.ncbi.nlm.nih.gov/pubmed/27148690
http://dx.doi.org/10.1038/cddis.2016.120

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