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Transcription factor Six2 mediates the protection of GDNF on 6-OHDA lesioned dopaminergic neurons by regulating Smurf1 expression
Glial cell line-derived neurotrophic factor (GDNF) has strong neuroprotective and neurorestorative effects on dopaminergic (DA) neurons in the substantia nigra (SN); however, the underlying molecular mechanisms remain to be fully elucidated. In this study, we found that the expression level of trans...
Autores principales: | Gao, J, Kang, X-y, Sun, S, Li, L, Zhang, B-l, Li, Y-q, Gao, D-s |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917658/ https://www.ncbi.nlm.nih.gov/pubmed/27148690 http://dx.doi.org/10.1038/cddis.2016.120 |
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