Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria

Secretory IgA (SIgA) directed against gut resident bacteria enables the mammalian mucosal immune system to establish homeostasis with the commensal gut microbiota after weaning. Germinal centers (GCs) in Peyer's patches (PPs) are the principal inductive sites where naive B cells specific for ba...

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Detalles Bibliográficos
Autores principales: Rios, D, Wood, M B, Li, J, Chassaing, B, Gewirtz, A T, Williams, I R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917673/
https://www.ncbi.nlm.nih.gov/pubmed/26601902
http://dx.doi.org/10.1038/mi.2015.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917673/
https://www.ncbi.nlm.nih.gov/pubmed/26601902
http://dx.doi.org/10.1038/mi.2015.121

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