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Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria
Secretory IgA (SIgA) directed against gut resident bacteria enables the mammalian mucosal immune system to establish homeostasis with the commensal gut microbiota after weaning. Germinal centers (GCs) in Peyer's patches (PPs) are the principal inductive sites where naive B cells specific for ba...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917673/ https://www.ncbi.nlm.nih.gov/pubmed/26601902 http://dx.doi.org/10.1038/mi.2015.121 |