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Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy

Background. Epithelial-mesenchymal transition (EMT) of retinal pigment epithelium (RPE) is vital in proliferative vitreoretinopathy (PVR) development. Apoptosis-stimulating proteins of p53 (ASPP2) have recently been reported to participate in EMT. However, the role of ASPP2 in PVR pathogenesis has n...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Li, Bai, Yu-Jing, Hu, Qin-Rui, Li, Shan-Shan, Huang, Lv-Zhen, Li, Xiao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917715/
https://www.ncbi.nlm.nih.gov/pubmed/27378826
http://dx.doi.org/10.1155/2016/7920631