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Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex123

Cerebral neocortex development in mammals requires highly orchestrated events involving proliferation, differentiation, and migration of neural progenitors and neurons. Rapgef2 and Rapgef6 constitute a unique family of guanine nucleotide exchange factors for Rap1 small GTPase, which is known to play...

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Detalles Bibliográficos
Autores principales: Maeta, Kazuhiro, Edamatsu, Hironori, Nishihara, Kaori, Ikutomo, Junji, Bilasy, Shymaa E., Kataoka, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917737/
https://www.ncbi.nlm.nih.gov/pubmed/27390776
http://dx.doi.org/10.1523/ENEURO.0142-16.2016