pH-Selective Cytotoxicity of pHLIP-Antimicrobial Peptide Conjugates

Positively charged antimicrobial peptides have become promising agents for the treatment of cancer by inducing apoptosis though their preferential binding and disruption of negatively charged membranes, such as the mitochondrial membrane. (KLAKLAK)(2) is such a peptide but due to its polarity, it ca...

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Detalles Bibliográficos
Autores principales: Burns, Kelly E., McCleerey, Tanner P., Thévenin, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917822/
https://www.ncbi.nlm.nih.gov/pubmed/27334357
http://dx.doi.org/10.1038/srep28465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917822/
https://www.ncbi.nlm.nih.gov/pubmed/27334357
http://dx.doi.org/10.1038/srep28465

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