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pH-Selective Cytotoxicity of pHLIP-Antimicrobial Peptide Conjugates
Positively charged antimicrobial peptides have become promising agents for the treatment of cancer by inducing apoptosis though their preferential binding and disruption of negatively charged membranes, such as the mitochondrial membrane. (KLAKLAK)(2) is such a peptide but due to its polarity, it ca...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917822/ https://www.ncbi.nlm.nih.gov/pubmed/27334357 http://dx.doi.org/10.1038/srep28465 |