Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue

INTRODUCTION: The nicotinic α5 receptor subunit, encoded by CHRNA5, harbors multiple functional single nucleotide polymorphisms (SNPs) that affect mRNA expression and alter the encoded protein. These polymorphisms are most notably associated with drug-taking behaviors and cognition. We previously id...

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Detalles Bibliográficos
Autores principales: Ramsay, Jessica E., Rhodes, C. Harker, Thirtamara-Rajamani, Keerthi, Smith, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917931/
https://www.ncbi.nlm.nih.gov/pubmed/27350810
http://dx.doi.org/10.1186/s41021-015-0020-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917931/
https://www.ncbi.nlm.nih.gov/pubmed/27350810
http://dx.doi.org/10.1186/s41021-015-0020-x

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