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Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue
INTRODUCTION: The nicotinic α5 receptor subunit, encoded by CHRNA5, harbors multiple functional single nucleotide polymorphisms (SNPs) that affect mRNA expression and alter the encoded protein. These polymorphisms are most notably associated with drug-taking behaviors and cognition. We previously id...
Autores principales: | Ramsay, Jessica E., Rhodes, C. Harker, Thirtamara-Rajamani, Keerthi, Smith, Ryan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917931/ https://www.ncbi.nlm.nih.gov/pubmed/27350810 http://dx.doi.org/10.1186/s41021-015-0020-x |
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