Presynaptic muscarinic acetylcholine autoreceptors (M(1), M(2) and M(4) subtypes), adenosine receptors (A(1) and A(2A)) and tropomyosin-related kinase B receptor (TrkB) modulate the developmental synapse elimination process at the neuromuscular junction

BACKGROUND: The development of the nervous system involves an initially exuberant production of neurons that make an excessive number of synaptic contacts. The initial overproduction of synapses promotes connectivity. Hebbian competition between axons with different activities (the least active are...

Descripción completa

Detalles Bibliográficos
Autores principales: Nadal, Laura, Garcia, Neus, Hurtado, Erica, Simó, Anna, Tomàs, Marta, Lanuza, Maria A., Santafé, Manel, Tomàs, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917939/
https://www.ncbi.nlm.nih.gov/pubmed/27339059
http://dx.doi.org/10.1186/s13041-016-0248-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917939/
https://www.ncbi.nlm.nih.gov/pubmed/27339059
http://dx.doi.org/10.1186/s13041-016-0248-9

Ejemplares similares