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multiDE: a dimension reduced model based statistical method for differential expression analysis using RNA-sequencing data with multiple treatment conditions

BACKGROUND: The growing complexity of biological experiment design based on high-throughput RNA sequencing (RNA-seq) is calling for more accommodative statistical tools. We focus on differential expression (DE) analysis using RNA-seq data in the presence of multiple treatment conditions. RESULTS: We...

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Detalles Bibliográficos
Autores principales: Kang, Guangliang, Du, Li, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917940/
https://www.ncbi.nlm.nih.gov/pubmed/27334001
http://dx.doi.org/10.1186/s12859-016-1111-9