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The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels

The bacterial mechanosensitive channel MscL gates in response to membrane tension as a result of mechanical force transmitted directly to the channel from the lipid bilayer. MscL represents an excellent model system to study the basic biophysical principles of mechanosensory transduction. However, u...

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Detalles Bibliográficos
Autores principales: Bavi, Navid, Cortes, D. Marien, Cox, Charles D., Rohde, Paul R., Liu, Weihong, Deitmer, Joachim W., Bavi, Omid, Strop, Pavel, Hill, Adam P., Rees, Douglas, Corry, Ben, Perozo, Eduardo, Martinac, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917966/
https://www.ncbi.nlm.nih.gov/pubmed/27329693
http://dx.doi.org/10.1038/ncomms11984