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The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels
The bacterial mechanosensitive channel MscL gates in response to membrane tension as a result of mechanical force transmitted directly to the channel from the lipid bilayer. MscL represents an excellent model system to study the basic biophysical principles of mechanosensory transduction. However, u...
Autores principales: | Bavi, Navid, Cortes, D. Marien, Cox, Charles D., Rohde, Paul R., Liu, Weihong, Deitmer, Joachim W., Bavi, Omid, Strop, Pavel, Hill, Adam P., Rees, Douglas, Corry, Ben, Perozo, Eduardo, Martinac, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917966/ https://www.ncbi.nlm.nih.gov/pubmed/27329693 http://dx.doi.org/10.1038/ncomms11984 |
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