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TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy

BACKGROUND: TNF weakly inducer of apoptosis (TWEAK) is member of the TNF ligand superfamily. Various data support that TWEAK produced by synovial macrophages may contribute to synovitis observed in psoriatic arthritis (PsoA). In PsoA, anti-TNF therapy has been successful in agreement with the key ro...

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Detalles Bibliográficos
Autores principales: Guis, Sandrine, Berbis, Philippe, Stephan, Delphine, Bertin, Daniel, Amatore, Florent, Balandraud, Nathalie, Lesavre, Nathalie, Desplat-Jégo, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917994/
https://www.ncbi.nlm.nih.gov/pubmed/27338143
http://dx.doi.org/10.1186/s12967-016-0923-8