An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions

INTRODUCTION: A wide variety of DNA lesions such as ultraviolet light-induced photoproducts and chemically induced bulky adducts and crosslinks (intrastrand and interstrand) interfere with replication and lead to mutations and cell death. In the human body, these damages may cause cancer, inborn dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Sonohara, Yuina, Iwai, Shigenori, Kuraoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918014/
https://www.ncbi.nlm.nih.gov/pubmed/27350805
http://dx.doi.org/10.1186/s41021-015-0014-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918014/
https://www.ncbi.nlm.nih.gov/pubmed/27350805
http://dx.doi.org/10.1186/s41021-015-0014-8

Ejemplares similares