Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages

INTRODUCTION: To examine whether the mutagenic potential of lung exposure to air-borne environmental mutagens is age dependent, we administered 1 mg of benzo[a]pyrene intratracheally to 11- and 24-month old (middle-aged and old, respectively) gpt delta transgenic mice that harbor gpt (guanine phosph...

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Detalles Bibliográficos
Autores principales: Aoki, Yasunobu, Hashimoto, Akiko H., Sugawara, Yoshiki, Hiyoshi-Arai, Kyoko, Goto, Sataro, Masumura, Kenichi, Nohmi, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918024/
https://www.ncbi.nlm.nih.gov/pubmed/27350804
http://dx.doi.org/10.1186/s41021-015-0004-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918024/
https://www.ncbi.nlm.nih.gov/pubmed/27350804
http://dx.doi.org/10.1186/s41021-015-0004-x

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