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A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT(2B) receptor antagonist AM1030

BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by highly pruritic eczematous lesions that are commonly treated with topical corticosteroids and calcineurin inhibitors. Side-effects and safety concerns associated with these agents restrict their use, and new,...

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Detalles Bibliográficos
Autores principales: Palmqvist, Niklas, Siller, Max, Klint, Cecilia, Sjödin, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918035/
https://www.ncbi.nlm.nih.gov/pubmed/27340371
http://dx.doi.org/10.1186/s12950-016-0127-2