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A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT(2B) receptor antagonist AM1030
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by highly pruritic eczematous lesions that are commonly treated with topical corticosteroids and calcineurin inhibitors. Side-effects and safety concerns associated with these agents restrict their use, and new,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918035/ https://www.ncbi.nlm.nih.gov/pubmed/27340371 http://dx.doi.org/10.1186/s12950-016-0127-2 |