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Neonatal exposure of 17β-estradiol has no effects on mutagenicity of 7,12-dimethylbenz [a] anthracene in reproductive tissues of adult mice

INTRODUCTION: Biological studies in animals and epidemiological findings in humans clearly demonstrate that estrogens including 17β-estradiol (E2) are weak carcinogens via both genetic and epigenetic mechanisms. Carcinogenesis analyses have indicated that female mice exposed to E2 as neonates develo...

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Detalles Bibliográficos
Autores principales: Zhang, Zhuhong, Li, Haifang, Manjanatha, Mugimane G., Chen, Tao, Mei, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918036/
https://www.ncbi.nlm.nih.gov/pubmed/27350812
http://dx.doi.org/10.1186/s41021-015-0011-y