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The effect of n-3 polyunsaturated fatty acids on incidence and severity of oxaliplatin induced peripheral neuropathy: a randomized controlled trial

BACKGROUND: Oxaliplatin induced peripheral neurotoxicity (OXIPN) is the major dose-limiting and long-lasting side effect of oxaliplatin. N-3 PUFAs have neuroprotective property via their effects on voltage-gated ion channels and by reducing the production of proinflammatory cytokines that causes neu...

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Detalles Bibliográficos
Autores principales: Esfahani, Ali, Somi, Mohammad hossein, Ayromlou, Hormoz, Nikanfar, Alireza, Jafarabadi, Mohammad Asghari, Sadat, Bina Eftekhar, Ghoreishi, Zohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918070/
https://www.ncbi.nlm.nih.gov/pubmed/27340553
http://dx.doi.org/10.1186/s40364-016-0066-3