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Inflammatory conditions partly impair the mechanically mediated activation of Smad2/3 signaling in articular cartilage
BACKGROUND: Joint trauma, which is frequently related with mechanical overloading of articular cartilage, is a well-established risk for osteoarthritis (OA) development. Additionally, reports show that trauma leads to synovial joint inflammation. In consequence, after joint trauma, cartilage is infl...
Autores principales: | Madej, Wojciech, Buma, Pieter, van der Kraan, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918093/ https://www.ncbi.nlm.nih.gov/pubmed/27334538 http://dx.doi.org/10.1186/s13075-016-1038-6 |
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