Progressive impairment of Ca(V)1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder that is typically fatal within 3–5 years of diagnosis. While motoneuron death is the defining characteristic of ALS, the events that underlie its pathology are not restricted to the nervous system. In this r...

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Detalles Bibliográficos
Autores principales: Beqollari, Donald, Romberg, Christin F., Dobrowolny, Gabriella, Martini, Martina, Voss, Andrew A., Musarò, Antonio, Bannister, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918102/
https://www.ncbi.nlm.nih.gov/pubmed/27340545
http://dx.doi.org/10.1186/s13395-016-0094-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918102/
https://www.ncbi.nlm.nih.gov/pubmed/27340545
http://dx.doi.org/10.1186/s13395-016-0094-6

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