MUFFINN: cancer gene discovery via network analysis of somatic mutation data

A major challenge for distinguishing cancer-causing driver mutations from inconsequential passenger mutations is the long-tail of infrequently mutated genes in cancer genomes. Here, we present and evaluate a method for prioritizing cancer genes accounting not only for mutations in individual genes b...

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Detalles Bibliográficos
Autores principales: Cho, Ara, Shim, Jung Eun, Kim, Eiru, Supek, Fran, Lehner, Ben, Lee, Insuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918128/
https://www.ncbi.nlm.nih.gov/pubmed/27333808
http://dx.doi.org/10.1186/s13059-016-0989-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918128/
https://www.ncbi.nlm.nih.gov/pubmed/27333808
http://dx.doi.org/10.1186/s13059-016-0989-x

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