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Increased tauopathy drives microglia-mediated clearance of beta-amyloid

Alzheimer disease is characterized by the accumulation of β-amyloid (Aβ) plaques and tau-laden neurofibrillary tangles. Emerging studies suggest that in neurodegenerative diseases, aggregation of one protein species can promote other proteinopathies and that inflammation plays an important role in t...

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Detalles Bibliográficos
Autores principales: Chen, Wesley, Abud, Edsel A., Yeung, Stephen T., Lakatos, Anita, Nassi, Trevor, Wang, Jane, Blum, David, Buée, Luc, Poon, Wayne W., Blurton-Jones, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918195/
https://www.ncbi.nlm.nih.gov/pubmed/27339073
http://dx.doi.org/10.1186/s40478-016-0336-1