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Increased tauopathy drives microglia-mediated clearance of beta-amyloid
Alzheimer disease is characterized by the accumulation of β-amyloid (Aβ) plaques and tau-laden neurofibrillary tangles. Emerging studies suggest that in neurodegenerative diseases, aggregation of one protein species can promote other proteinopathies and that inflammation plays an important role in t...
Autores principales: | Chen, Wesley, Abud, Edsel A., Yeung, Stephen T., Lakatos, Anita, Nassi, Trevor, Wang, Jane, Blum, David, Buée, Luc, Poon, Wayne W., Blurton-Jones, Mathew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918195/ https://www.ncbi.nlm.nih.gov/pubmed/27339073 http://dx.doi.org/10.1186/s40478-016-0336-1 |
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