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Immunotherapy for the treatment of Alzheimer’s disease: amyloid-β or tau, which is the right target?
Alzheimer’s disease (AD) is characterized by the presence of amyloid plaques composed mainly of amyloid-β (Aβ) protein. Overproduction or slow clearance of Aβ initiates a cascade of pathologic events that may lead to formation of neurofibrillary tangles, neuronal cell death, and dementia. Although i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918231/ https://www.ncbi.nlm.nih.gov/pubmed/27471697 http://dx.doi.org/10.2147/ITT.S40131 |