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Enhancement of antibody-dependent cell mediated cytotoxicity: a new era in cancer treatment

The therapeutic efficacy of some anti-tumor monoclonal antibodies (mAbs) depends on the capacity of the mAb to recognize the tumor-associated antigen and induce cytotoxicity via a network of immune effector cells. This process of antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cel...

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Detalles Bibliográficos
Autores principales: Rajasekaran, Narendiran, Chester, Cariad, Yonezawa, Atsushi, Zhao, Xing, Kohrt, Holbrook E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918249/
https://www.ncbi.nlm.nih.gov/pubmed/27471715
http://dx.doi.org/10.2147/ITT.S61292