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Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. The treatment options for patients with advanced HCC are limited, and novel treatment strategies are required urgently. Glypican-3 (GPC3), a member of the glypican family of heparan sulfate proteoglycans, is overex...

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Detalles Bibliográficos
Autores principales: Ofuji, Kazuya, Saito, Keigo, Yoshikawa, Toshiaki, Nakatsura, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918265/
https://www.ncbi.nlm.nih.gov/pubmed/27508174
http://dx.doi.org/10.2147/JHC.S48517